Evaluation of Innotrac Aio! Second-Generation Cardiac Troponin I Assay: The Main Characteristics for Routine Clinical Use

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Evaluation of Innotrac Aio! Second-Generation Cardiac Troponin I Assay: The Main Characteristics for Routine Clinical Use

The availability of a simple, sensitive, and rapid test using whole blood to facilitate processing and to reduce the turnaround time could improve the management of patients presenting with chest pain. The aim of this study was an evaluation of the Innotrac Aio! second-generation cardiac troponin I (cTnI) assay. The Innotrac Aio! second-generation cTnI assay was compared with the Abbott AxSYM f...

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Innotrac aio! Second-generation cardiac troponin I assay: imprecision profile and other key characteristics for clinical use.

To the Editor: Cardiac troponin has been designated as the preferred biomarker for diagnosis of myocardial infarction (MI) (1 ). Previously published data, however, confirm the large diversity among cardiac troponin assays with respect to important analytical characteristics, including assay standardization, antibody specificity, interferences, and assay imprecision, and underscore the need for...

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Multicenter evaluation of a second-generation assay for cardiac troponin T.

We report on the evaluation of the second-generation assay for cardiac troponin T (cTnT) on the Enzymun system. This new assay is completely specific for the cardiac isoform of TnT, utilizing two cardiospecific monoclonal antibodies. The assay time is reduced to 45 min. The interassay precision shows a median CV of 5.5%; 20% interassay CV was found between 0.05 and 0.1 microg/L. The cardiosensi...

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A Rational Adoption of the High Sensitive Assay for Cardiac Troponin I in Diagnostic Routine

We describe the adoption of high sensitive troponin I (hsTnI) in clinical practice in two hospital settings in Italy. Samples from 426 consecutive patients (mean age 68.8 ± 17.0) admitted to the Emergency Department with a suspected acute coronary syndrome (ACS) have been tested at admittance and after 3 and 6 hours by contemporary TnI and hsTnI. Results have been compared to the final clinical...

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Analytical performance of the i-STAT cardiac troponin I assay.

BACKGROUND This study determines the analytical characteristics of the i-STAT cardiac troponin I assay (cTnI; i-STAT, Princeton, NJ), a 10-min POC assay, designed to be performed at the bedside. METHODS Three different hospitals participated in a patient specimen and analytical validation study (n=186) for the i-STAT cTnI assay carried out in real time. A total of 186 whole blood specimens (l...

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ژورنال

عنوان ژورنال: Journal of Automated Methods and Management in Chemistry

سال: 2006

ISSN: 1463-9246,1464-5068

DOI: 10.1155/jammc/2006/39325